Critical Re-evaluation of Metabolic Pathway Intermodulation: Unraveling Crosstalk Mechanisms in Cellular Bioenergetics

Authors

  • Isla King Professor
  • Kai Edwards Associate Professor
  • Nico Jackson PhD

Keywords:

Metabolic Pathway Intermodulation, Cellular Bioenergetics, Crosstalk Mechanisms, Glycolytic Flux, Oxidative Phosphorylation, Advanced Omics, Bioinformatics, Therapeutic Targets, Metabolic Disorders

Abstract

This study delves into the intricate complexities of metabolic pathway intermodulation, focusing on the crosstalk mechanisms within cellular bioenergetics. Utilizing advanced omics technologies and bioinformatics tools, we elucidate the interdependency of glycolytic flux and oxidative phosphorylation. Our findings reveal novel insights into pathway interactions that are pivotal for cellular homeostasis, offering promising therapeutic targets for metabolic disorders.

Author Biographies

Isla King, Professor

Professor
University of Cambridge
The Old Schools, Trinity Ln, Cambridge CB2 1TN, United Kingdom

Kai Edwards, Associate Professor

Associate Professor
University of Toronto
27 King's College Cir, Toronto, ON M5S, Canada

Nico Jackson, PhD

PhD
University of Melbourne
Parkville, VIC 3010, Australia

References

Sharma, V., Zheng, W., Huang, J., & Cook, D. E. (2020). CRISPR-Cas RNA targeting using transient Cas13a expression in Nicotiana benthamiana. In RNA Abundance Analysis: Methods and Protocols (pp. 1-18). New York, NY: Springer US.

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Published

2024-01-17

Issue

Vol. 2 No. 1 (2024)

Section

Articles