A Comparative Analysis of Genetic and Epigenetic Modifications: Unraveling Competing Paradigms in Oncogenic Pathways

Quinn Baker; Sophia Ward; Pat Green; Skyler Smith

Authors

Quinn Baker PhD
Sophia Ward Professor
Pat Green Dr. Sc
Skyler Smith Associate Professor

Keywords:

Oncogenic Pathways, Genetic Mutations, Epigenetic Alterations, Multi-omics, Precision Oncology

Abstract

Recent advancements in molecular biology have accentuated the intricate interplay between genetic mutations and epigenetic alterations in oncogenesis. This study employs a multi-omics approach to dissect these modifications, utilizing high-throughput sequencing and bioinformatics tools. Our findings elucidate distinct epigenetic signatures that complement mutational landscapes, providing insights into personalized cancer therapies. The comparative paradigm analysis underscores the potential of integrating omics data for precision oncology applications.

Author Biographies

Quinn Baker, PhD

PhD
Harvard University
Massachusetts Hall, Cambridge, MA 02138, United States

Sophia Ward, Professor

Professor
University of Oxford
Wellington Square, Oxford OX1 2JD, United Kingdom

Pat Green, Dr. Sc

Dr. Sc
Ludwig Maximilian University of Munich
Geschwister-Scholl-Platz 1, 80539 München, Germany

Skyler Smith, Associate Professor

Associate Professor
University of Toronto
27 King's College Circle, Toronto, Ontario M5S 1A1, Canada

References

Sharma, V., Devendran, R., Kumar, M., Prajapati, R., Kumar, R., & Prakash, V. (2025). Molecular dynamics of plant-virus interactions: unravelling the dual role of ubiquitin proteasome system. Stress Biology, 5(1), 12.